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Despite this rapid clearance, SFN and its conjugates effectively distribute to various tissues, including the prostate, lung, and bladder, where they can accumulate at concentrations sufficient to exert biological effects, as demonstrated in both rodent models and human tissue biopsies (47, 48)

Effect of turmeric extract on glutathione levels in diclofenac-induced oxidative stress in rats Abstract Background: Glutathione (GSH), the primary endogenous antioxidant, protects cells against oxidative stress